Mechanosensitive Ion Channels
Andre Kamkin, Irina Kiseleva, Ilya Lozinsky (auth.), Andre Kamkin, Irina Kiseleva (eds.)This book is devoted to discussing the latest data dealing with mechanosensitive channels research results.
It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and mechanosensitive signaling cascades research.
Key problems of cell mechanobiology are also discussed.
The reviews included here deal with experimental methods of studying mechanosensitive channels, role of lipid bilayer mechanics in mechanosensation, molecular organization, physiology and pharmacology of various channels reacting to membrane tension as a stimulus.
The book also examines mechanotransduction, which the authors define as the biochemical response of cells to mechanical stimulation.
As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.
The book presents not only the latest achievements in the field but also brings the understanding of the problem closer to the experts in related medical and biological sciences as well as practicing doctors.